The 2006 Liberty Flames football team represented Liberty University a member of the Big South Conference during the 2006 NCAA Division I FCS football season.

Led by first-year head coach Danny Rocco, the Flames compiled an overall record of 6–5 with a mark of 2–2 in conference play, placing in a three-way tie for second in the Big South.

Liberty played home games at Williams Stadium in Lynchburg, Virginia.

Following the firing of former coach Ken Karcher, who headed the Liberty football team from 2000 to 2005, the Flames announced Rocco as their new head coach on December 2, 2005.

This college football 2000s season article is a stub.