The 2006 North Dakota State Bison football team represented North Dakota State University in the 2006 NCAA Division I FCS football season.

The Bison play at the Fargodome in Fargo, North Dakota.

North Dakota State competes in the FCS division of college football.

[1] While being ranked #4 at the end of the year, NDSU was ineligible to make the playoffs per NCAA Division I rules which mandates a four-year probationary period for new football programs (NDSU entered DI in 2004).

The 2006 Bison team had a stout defense that held their opponents to 13.4 points per game and were ranked among the top teams to end the year.