The 2006 Elections for the Pennsylvania State Senate were held on November 7, 2006, with even-numbered districts being contested.

[4] The Senate elections saw no seats change parties, with the Republicans holding onto an eight-seat majority.

Senate Republican floor leader, David J. Brightbill, was defeated for in the primary election by tire salesman Mike Folmer.

President pro tempore Robert C. Jubelirer was defeated for re-election by fellow Republican and Blair County commissioner John Eichelberger.

Three Republican senators, Joe Conti, Charles D. Lemmond Jr., Noah W. Wenger, retired and were succeeded by Chuck McIlhinney, Lisa Baker, and Michael W. Brubaker, respectively.