Trent Lott Republican Trent Lott Republican The 2006 United States Senate election in Mississippi was held November 7, 2006.

Incumbent Republican Trent Lott won re-election to a fourth term.

Lott ran for re-election without facing any opposition in his party's primary.

While it had been speculated that Lott might retire after his home was destroyed in Hurricane Katrina, he instead chose to run for re-election.

Fleming is an African American, which represents 37% of the state's population.