Mike DeWine Republican Sherrod Brown Democratic The 2006 United States Senate election in Ohio was held November 7, 2006.

Phil Singer, a spokesman for the Democratic Senatorial Campaign Committee said, "Mike DeWine Senior is in for the fight of his life, make no mistake about it.

"[4] On July 14, 2006, DeWine's campaign began airing TV commercials depicting a smoking World Trade Center.

"[5][6] DeWine's campaign admitted that the video was actually a still photo of the World Trade Center with smoke digitally added.

This claim led to the Associated Press reporting on October 19 that, "Several Ohio television stations have stopped airing a Republican ad because state documents contradict the ad's accusation that Democratic U.S. Senate candidate Sherrod Brown didn't pay an unemployment tax bill for 13 years."

DeWine's narrow 2,000 vote victory in Hamilton County which is home to Cincinnati, came nowhere close to making a dent in Brown's lead.