The 2006 Vuelta a Castilla y León was the 21st edition of the Vuelta a Castilla y León cycle race and was held on 20 March to 24 March 2006.

The race started in Valladolid and finished in Segovia.

[2][3] The race was won by Alexander Vinokourov.

Fifteen teams of up to eight riders started the race:[3]

This cycling race article related to Spanish cycling is a stub.