The 2007–08 Liga Artzit season began on 17 August 2007 and 24 May 2008.
Hapoel Jerusalem won the title and were promoted to Liga Leumit alongside runners-up Maccabi Ironi Kiryat Ata.
Maccabi HaShikma Ramat Hen and Hapoel Kfar Shalem were relegated to Liga Alef