Managed by Terry Francona, the Red Sox finished first in the American League East with a record of 96 wins and 66 losses.

In the ALCS, the Red Sox defeated the American League Central champion Cleveland Indians in seven games, despite falling behind 3–1 in the series.

Advancing to the World Series, the Red Sox swept the National League champion Colorado Rockies, to capture their second championship in four years.

[1] On November 14, 2006, Major League Baseball announced that the Red Sox had competed for the rights to negotiate a contract with Japanese pitcher Daisuke Matsuzaka.

Papelbon wanted to re-fill that spot, and team officials believed he had rehabilitated himself so well in the offseason that his health of this shoulder was no longer a concern, and allowed him to return to the bullpen.

The Red Sox pursued J. D. Drew, who had recently opted out of the remainder of his contract with the Los Angeles Dodgers to become a free agent.

At the end of spring training of 2007, the Red Sox traded minor league veteran catcher Alberto Castillo for Baltimore Orioles outfielder Cory Keylor.

While their 96–66 record was the same as that of the Cleveland Indians, the Red Sox held the season series tiebreaker for American League home-field advantage, having bested the Tribe 5 games to 2.

Although Kevin Youkilis hit a solo home run in the first inning that would prove to be all the offense Beckett needed, David Ortiz provided additional support with a two-run homer in the third to cap off a 4–0 Game 1 victory.

In the bottom of the ninth, after a Julio Lugo single and David Ortiz's playoff record-tying fourth walk of the night (this time, intentional), Manny Ramírez ended the game with a towering home run that left Fenway Park over the Green Monster.

In Game 3, Curt Schilling brought back the dominant pitching, scattering six hits and striking out four in seven innings of shutout work.

The game drew into extra frames, but the Red Sox bullpen got hammered in the top of the eleventh, with Éric Gagné, Javier López and Jon Lester giving up seven runs.

In Game 3, Daisuke Matsuzaka gave up 4 runs, and Jason Varitek provided the only Red Sox offense with a two-run homer in the seventh, as the Indians took the Jacobs Field opener, 4–2, for a 2–1 series lead.

Game 4 did not start much better for the Red Sox, with a seven-run fifth inning that saw Manny Delcarmen allow four runs (two charged to starter Tim Wakefield).

In the top of the sixth, the Sox showed some life with back-to-back-to-back solo home runs by Kevin Youkilis, David Ortiz and Manny Ramírez.

His comments seemed laissez faire at the time, as many members of the Boston media chose to interpret them as meaning that Manny would not put forth his best effort in the games to come and would thus disrupt his team's ability to compete.

After going the distance with the Indians, the Red Sox had to face the red-hot Colorado Rockies, who had just finished a 21-of-22 run that included forcing and winning a Wild Card one-game playoff with the San Diego Padres, then sweeping the Philadelphia Phillies in the NLDS and the Arizona Diamondbacks in the NLCS.

With a 2–1 Game 2 win, the Red Sox went to Coors Field in Denver with the advantage, hoping the rarefied air would not affect them too much.

In the eighth inning, Bobby Kielty hit a pinch-hit home run to put an end to the Sox's scoring.

Two days later, on October 30, the Red Sox were the guests of honor in a Rolling Rally through Boston, after which the team began to lay their plans for the 2008 season.

Dustin Pedroia, Jacoby Ellsbury, Clay Buchholz, Daisuke Matsuzaka, and Hideki Okajima all had their moments and left their mark of this season in Red Sox history.

Pedroia also excelled his play in the postseason by 2 HR and driving in 10 runs in 14 games to help the Red Sox win the World Series.

On April 22, 2007, in a game against the New York Yankees, the Red Sox hit four consecutive home runs for the first time in franchise history (and the fifth time in major league history),[17] when Manny Ramírez, J. D. Drew, Mike Lowell, and Jason Varitek all hit home runs off Yankees pitcher Chase Wright.

Drew also hit the second of four consecutive home runs the last time this happened, when the Los Angeles Dodgers did it against the San Diego Padres on September 18, 2006.

David Ortiz was elected to start at first base by the fans, third baseman Mike Lowell and outfielder Manny Ramírez were chosen by their fellow players as reserves.

Julio Lugo and Coco Crisp became the first pair of Red Sox players to have at least 25 stolen bases since Tris Speaker and Hal Janvrin in 1914.

[20] Leading the league with a perfect 1.000 fielding percentage, and an AL-record 1,079 errorless chances at first, Kevin Youkilis won the 2007 AL Gold Glove award for first basemen.