The Challenge Cup is the most prestigious knock-out competition in the world of rugby league, featuring teams from across Europe including England, Scotland, Wales, France and Russia.

Castleford Lock Lane defeated Bradford Dudley Hill after extra time in the closest game of this round, which against consisted of amateur teams.

2005 semi-finalists Toulouse failed to win at York, though Pia's victory against Blackpool ensured that one team from the French Rugby League Championship progressed.

Celtic Crusaders' defeat saw the final Welsh team leave the tournament.

Pia's defeat saw the French rugby league championship's exit from the Cup.