The issue of the state's response to Hurricane Katrina played a large part in the decision of incumbent governor Kathleen Blanco to retire rather than seek a second term in office.

Term limits also effected many retirements in the state legislature, which proved to be a benefit to Republicans, who made gains in both houses.

He was opposed by two Republicans, country musician Sammy Kershaw and State Representative Gary Beard, and by two Independents, Norris "Spanky" Gros Jr. and Thomas D. Kates.

Incumbent Attorney General Charles Foti was challenged by both a Democrat, James "Buddy" Caldwell, and a Republican, Royal Alexander.

Bob Odom Democratic Mike Strain Republican Longtime incumbent Democrat Bob Odom faced his toughest re-election campaign ever, winning only 41% of the vote and ending up into a runoff with Republican State Representative Michael G. Strain.