In their 13th and final season under head coach Lloyd Carr, the Wolverines compiled a 9–4 record (6–2 in conference games), finished in a tie for second place in the Big Ten, and outscored opponents by a total of 354 to 278.

Four Michigan players received first-team honors on the 2007 All-Big Ten Conference football team: Jake Long (Coaches-1, Media-1); Chad Henne (Coaches-1); Mario Manningham (Coaches-1, Media-1); and guard Adam Kraus (Coaches-1, Media-1).

On March 25, Coach Lloyd Carr announced that TE Carson Butler, DE Eugene Germany, and DB Chris Richards had been dismissed for violations of team policy.

[1] Carr also had stated that WR Adrian Arrington had been suspended for the spring practice session due to a violation of team policy.

[6] Michigan started out strong, finishing the first quarter 14–7, but the Mountaineers scored 21 unanswered points to go up 28–14 just before halftime.

However, after the teams traded possessions, the Mountaineers drove 69 yards in 11 plays, and Julian Rauch connected on a 24-yard field goal with 26 seconds remaining in the contest to give ASU a 34–32 lead.

Then, shocking the College Football world, Appalachian State's Corey Lynch blocked the kick with 6 seconds left to seal the huge upset.

The Michigan fans booed the Wolverines on their home field and people were calling for Head Coach Lloyd Carr to be fired.

In addition to the huge defeat, Michigan lost its senior QB Chad Henne to a knee injury for two games due to a play in the second quarter.

ESPN reported, "A week after getting stunned by Appalachian State, the Wolverines were handed their worst beating since before Bo Schembechler worked the sideline at the Big House.

Dennis Dixon accounted for 368 yards and a career-high four touchdowns, helping the Ducks build a 25-point lead at halftime and cruise to an easy victory.

[10] Lloyd Carr faced many challenges, including the loss of his senior quarterback Chad Henne to a leg injury,[11] fans calling for his firing,[12] and his senior running back Mike Hart guaranteed a victory over the Irish.

In his second start freshmen QB Ryan Mallett was 16–29 passes and a rushing TD.

Despite a slow start and two early turnovers, the Wolverines extended their win streak to seven without Chad Henne or Mike Hart.

Michigan took the lead with a 62-yard drive, including a 37-yard run by Mike Hart and concluding with an 11-yard touchdown pass from Chad Henne to Mario Manningham with 3:54 remaining in the first quarter.

After Michigan safety Jamar Adams intercepted a Brian Hoyer pass, the Wolverines extended their lead with a 42-yard drive, including a 32-yard run by Hart and a five-yard touchdown pass from Henne to Carson Butler with 12:46 remaining in the half.

Michigan drove 79 yards in 48 seconds, aided by a personal foul penalty against Kendell Davis-Clark, and ending with a 14-yard pass from Henne to Greg Matthews with 6:47 remaining.

The defense then held the Spartans to a three-and-out, and the Wolverines drove 65 yards, including a third-and-eleven completion to Adrian Arrington, and ending with a third-and-twelve, 31-yard touchdown pass from Henne to Manningham at the 2:28 mark.

Florida was led by third-year head coach Urban Meyer and sophomore quarterback Tim Tebow, who won the 2007 Heisman Trophy weeks earlier.

Later in the quarter, Florida drove 59 yards, scoring on a nine-yard touchdown pass from Tebow to Percy Harvin.

[20][21][22] Late in the first quarter, a long punt return and a personal foul penalty gave Florida the ball at Michigan's 29-yard line; Florida took the lead on an 18-yard touchdown pass from Tebow to Andre Caldwell at the 14:48 mark of the second quarter.

[20][21][22] Michigan began the second half with a pooch kick, and Anton Campbell recovered the ball.