The tournament took place at the Tennis Center at Crandon Park in Key Biscayne, Florida, from March 21 through April 1, 2007.

Djokovic won his first Masters Series event of his career; whilst the resurgent Williams beat Henin for the only time in 2007.

Guillermo Cañas' ascent also continued, defeating Roger Federer for the second time in 6 days, and in two consecutive tournaments, making him the only man apart from Rafael Nadal to achieve this feat since 2003.

Fellow Argentine David Nalbandian also completed a double over Federer later in the year, beating him at the Madrid and Paris Masters.

The event also featured boys and girls junior singles tournaments, which were won by Kei Nishikori and Sorana Cîrstea respectively.