The 2007 Tour of Flanders cycle race was the 91st edition of this monumental classic and took place on April 8.

The day's break formed at kilometer 29 and included José Vicente García (Caisse d'Epargne), Laurent Mangel (AG2R), Enrico Franzoi (Lampre), Maarten Tjallingii (Skil-Shimano), Aleksandr Kuschynski (Liquigas), Evert Verbist (Chocolade Jacques) and David Boucher (Landbouwkrediet).

Shortly after the Berendries climb Fabian Cancellara made a successful move to bridge up to the break and was followed by Gert Steegmans.

Pre-race favourite Tom Boonen (Quick-Step–Innergetic) could not respond to the attack, perhaps due to his fall earlier in the race that hurt his knees and wrist.

Karsten Kroon and Tomas Vaitkus attempted to pursuit the two leaders but could not make it.