The competition took place at three locations in central Melbourne: the Melbourne Sports and Aquatic Centre (diving and water polo), St Kilda Beach (open water), and Rod Laver Arena in a temporary pool christened the Susie O'Neill Pool (synchro and swimming).
However, on 11 September 2007, the Court of Arbitration for Sport in Lausanne, Switzerland vacated these results imposing an 18-month competition ban on Mellouli, effective retroactively to 30 October 2006 for doping with amphetamine.
The Swimming competition comprised various events using all four strokes (Freestyle, Butterfly, Breaststroke and Backstroke) for men and women ranging in distance from 50 m up to 1500 m. A total of 40 gold medals were available for the Championships.
Events were held at the indoor diving pool at the Melbourne Sports and Aquatic Centre.
The water polo tournaments were held at the 9,000-seat outdoor pool at the Melbourne Sports and Aquatic Centre, which was constructed for the 2006 Commonwealth Games swimming competition.