The season began on May 17, 2008, and concluded with the championship game on August 24, 2008.
Philadelphia finished ahead of Boston based on head-to-head record of 2–0.
The 2008 MLL All-Star Game was played on July 17 at INVESCO Field at Mile High in Denver, Colorado.
[16] Ryan Powell of Denver was named the game Most Valuable Player.
The 2008 NB Zip Major League Lacrosse Championship Weekend took place on August 23 and 24 at Harvard Stadium in Boston, Massachusetts.