The 2008 Missouri Democratic presidential primary took place on Super Tuesday, February 5, 2008, with 72 delegates at stake.

[1] However, Obama rallied from behind as the numbers began to come in from the heavily African American precincts in and around St. Louis to win by just under 12,000 votes.

Geographically, Clinton won 109 of the 115 counties in the state, while Obama carried St. Louis, Kansas City and the areas around the college towns of Columbia and Maryville.

Ironically, Roman Catholics in Missouri also supported Obama by a margin of 50-46; this religious bloc solidly favored Clinton nationwide.

Obama did best in and around St. Louis, particularly in the urbanized city with a substantial African American community which gave him 71.09 percent of the vote.

It is also fairly Democratic-leaning at the state level, going handily to Governor Jay Nixon in the Missouri Gubernatorial Election of 2008, and while Southeast Missouri was won by Republicans George W. Bush and John McCain from 2000–2008, the region gave Bill Clinton one of his largest margins of victory in 1992 and 1996.

The area has many of the demographics in Clinton's favor – it is predominantly white and made up of working-class individuals who tend to be politically moderate on several issues.

Democrats from Missouri's congressional delegation were evenly split, a true testament to the outcome of the primary.