The Orange were coached by Greg Robinson and played their home games at the Carrier Dome in Syracuse, New York.
Syracuse's number two receiver, Taj Smith, declared himself eligible for the NFL draft.
The Orange marched the ball 63 yards on its opening drive, settling for a 36-yard field goal.
SU's defense kept Northwestern at bay until late in the second quarter, but the offense provided the Wildcats first points.
Syracuse quarterback Andrew Robinson was called for intentional grounding in his own end zone, resulting in a safety.
The ensuing touchdown run from back Curtis Brinkley gave the Orange its second lead of the game 10–9.
The drive resulted in a missed field goal, as kicker Patrick Shadle hit the upright from 51 yards out.
[4] Syracuse defeated Football Championship Subdivision Northeastern, 30–21, behind a combined 245 yards and two touchdowns from tailbacks Doug Hogue and Curtis Brinkley.
Quarterback Cam Dantley completing 14 of 17 passes for 167 yards and one touchdown in his third straight start for the Orange.
[5] Pittsburgh tailback LaRod Stephens-Howling scored two touchdowns in the fourth quarter, Conor Lee kicked four field goals, and Pittsburgh scored 18 unanswered points in the fourth quarter to rally past Syracuse 34–24.
Although Syracuse outgained West Virginia 346–268, and SU tailback Curtis Brinkley rushed for 144 yards, the Orange (1–5, 0–2) didn't register a touchdown for the first time in the season.
The loss made the Orange ineligible to compete in a bowl game for the fourth straight year under coach Robinson.
Connecticut broke the game open after struggling to hold on to a 22–14 second half lead.
QB Cameron Dantley's 11-yard touchdown pass to Donte Davis with 42 seconds left proved to be the game winner, as the Irish lost to an eight-loss team for the first time in its school's storied history.