The 2009–10 Baylor Lady Bears women's basketball team were coached by Kim Mulkey.

The Bears were a member of the Big 12 Conference and participated in the Final Four.

Brittney Griner set numerous NCAA Division I, Big 12 Conference and Baylor records.

[7] The Lady Bears advanced to the Women's Final Four by defeating Duke 51-48.

In that game, Griner set a new NCAA Woman's tournament record by getting her 31st block, breaking the old record set by Alison Bales of Duke in 2006.