Following a famous 7–1 opening day win at Norwich City, manager Paul Lambert left Colchester for the Canaries under a storm surrounding compensation.

After beating Bromley and then Hereford United, Colchester faced Preston North End but were beaten 7–0 at Deepdale following five second half goals.

Incoming were Ashley Vincent, following a loan spell last season, as well as Lee Beevers, David Fox, Magnus Okuonghae and Ben Williams, all on permanent deals.

Three days prior to the season opener against Norwich City, the club announced the signing of former striker Kevin Lisbie on loan from Ipswich Town.

Norwich City contacted Robbie Cowling following the game asking to approach Lambert regarding their vacant manager position after they had sacked Bryan Gunn following the U's famous victory.

He enjoyed a nine game unbeaten run following his appointment, while making the loan signings of Danny Batth, Kayode Odejayi and John-Joe O'Toole.

In the FA Cup, the U's beat Bromley and Hereford United on their way to the third round, but were heavily beaten 7–0 at Deepdale by Preston North End in the game prior to their 5–0 home defeat by Norwich.