The 2009–10 Israel State Cup (Hebrew: גביע המדינה, Gvia HaMedina) was the 71st season of Israel's nationwide football cup competition and the 56th after the Israeli Declaration of Independence.
It started on 4 September 2009, while the final was held in Ramat Gan Stadium on 11 May 2010.
The competition was won by Hapoel Tel Aviv, who had beaten Bnei Yehuda 3–1 in the final.
Clubs participating in the Liga Alef gain entry in this round.
Clubs participating in the Israeli Premier League gain entry in this round.