The winners of each division got promoted to the 2010–11 Liga II season.
The bottom six from each division were relegated at the end of the season to the county football leagues (Liga IV).
To determine this team, separate standings were computed, using only the games played against the clubs ranked 1st through 11th.
CS Buftea sold its Liga II place to third tier club Săgeata Stejaru.
Liberty Salonta withdrew at the end of the season from Liga II, CFR Timișoara, which initially relegated, was spared from relegation.