From the 2009–10 season, Greek gambling giant Intralot became the Melbourne Victory's new major sponsor to replace Samsung in a two-year deal valued at $2 million.

[5] Moreover, José Luis López Ramírez's loan spell was terminated from Deportivo Saprissa[6] and Daniel Allsopp moved to Al Rayyan.

[15] On 1 December 2009, it was announced that Ney Fabiano was leaving Melbourne and had signed a contract with Thai Premier League team Bangkok Glass FC for the 2010 season.

[17] Melbourne Victory were drawn into Group E in the 2010 AFC Champions League along with Seongnam Ilhwa Chunma, Beijing Guoan and Kawasaki Frontale.

[18] With key players Archie Thompson, Matthew Kemp and Billy Celeski sidelined for long term injuries,[19][20][21] Victory finished bottom of Group E. Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.