The 2009–10 Moldovan National Division (Romanian: Divizia Națională) was the 19th season of top-tier football in Moldova.
On 6 June 2009, Tiligul-Tiras Tiraspol announced that the club would dissolve, citing a lack of funds as the reason.
The 2008–09 season had already been absolved with only eleven teams after FC Politehnica Chișinău withdrew their participation just days before the scheduled start.
The two vacant league spots were filled with 2008–09 Moldovan "A" Division champions Viitorul Orhei and 11th-placed Sfîntul Gheorghe, who bought their way into the top level.
Official schedule(in Romanian) Key numbers for pairing determination: