The 2009–10 South Dakota Coyotes men's basketball team represented the University of South Dakota in the 2009–10 NCAA Division I men's basketball season.

The Coyotes were led by head coach Dave Boots in his 22nd year leading the team.

South Dakota played their home games at the DakotaDome in Vermillion, South Dakota, as members of the Great West Conference.

As the top seed in the Great West tournament, South Dakota won two games, culminating in a 91-86 victory over Houston Baptist to win the Great West tournament championship.

[3] Instead, as the Great West champion, South Dakota was given an automatic bid[4] to the 2010 CIT.