The 2009–10 South Florida Bulls men's basketball team represented the University of South Florida Bulls during the 2009–10 NCAA Division I men's basketball season.

The team was coached by Stan Heath in his third year at the school.

The Bulls finished the season 20–13, 9–9 in Big East play.

They lost in the second round of the 2010 Big East men's basketball tournament to Georgetown and were invited to play in the 2010 National Invitation Tournament where they lost in the first round to North Carolina State.

In the Week 13 poll released on February 8, USF received two AP Poll votes (unofficially ranking them 44th), marking the first time in school history that the USF men’s basketball team has received votes in any rankings polls.