The 2009–10 USC Trojans men's basketball team represented the University of Southern California in the 2009–10 NCAA Division I men's basketball season.
The Trojans are a member of the Pacific-10 Conference.
USC finished the season 16–14 and 8–10 in the Pac-10 but did not participate in the 2010 Pacific-10 Conference men's basketball tournament due to self-imposed sanctions.