The 2009–10 Wyoming Cowboys basketball team[1] represented the University of Wyoming during the 2009–2010 NCAA Division I men's basketball season.

The Cowboys were coached by Heath Schroyer who was in his 3rd season and played their home games at the Arena-Auditorium in Laramie, Wyoming.

The Cowboys are a member of the Mountain West Conference.

They finished the season 10–21, 3–13 in Mountain West play and lost in the first round of the 2010 Mountain West Conference men's basketball tournament to Air Force.