Estudiantes de La Plata won the tie 4 points to 1 to earn their fourth Copa Libertadores title.
[1] Bold indicates winning years The final will be played over two legs, each at a finalists home venue.
Estudiantes started this year's Copa Libertadores run in the First Stage in a two-legged tie against Peruvian club Sporting Cristal for a spot in Group 5.
Playing in La Plata, Estudiantes won 4−0 with goals by Juan Sebastián Verón, Gastón Fernández, and Cristian Sánchez Prette (two).
Ramires scored for Cruzeiro before Giovanny Caicedo tied it for Deportivo Quito.
Estudiantes soundly won the match 4−0 thanks to a goal by Enzo Pérez and a hat-trick by Mauro Boselli.
Estudiantes' last match of group play ended in a scoreless tie against Universitario.
In the round of 16, they played against Chilean club Universidad de Chile (seeded 12).
Cruzeiro's quarterfinal match-up was against fellow Brazilian side São Paulo (seeded 4).
The first leg, played at home, was won 2−1 with goals by Leonardo Silva and Zé Carlos.
Wellington Paulista scored twice for Cruzeiro in as many minutes, but Grêmio came back and tied it in the second half.
As of the finals, Cruzeiro is the most effective team in the tournament, with an efficacy rating of 80.56% (9 wins, 2 draws, 1 loss).
In the first leg, played at home, Estudiantes won with a lone goal by Diego Galván.
Man of the Match: Fábio Assistant referees: Pablo Fandiño Mauricio Espinosa Fourth official: Martín Vázquez
Man of the Match: Juan Sebastián Verón Assistant referees: Patricio Basualto Francisco Mondría Fourth official: Pablo Pozo