The 2009 Copa Sudamericana de Clubes (officially the 2009 Copa Nissan Sudamericana de Clubes for sponsorship reasons) is the 8th edition of the CONMEBOL's secondary international club tournament.

Internacional were the defending champions, having won the trophy the previous season.

[1] This will also mark the last tournament in which Argentine clubs River Plate and Boca Juniors will be invited to participate without qualification.

Further changes include the additional allocation of berths (1) to all the countries except Brazil and Argentina.

[3] All teams, except for defending champion Internacional, entered the tournament in the First Stage.