Brisbane Roar finished Premiers with two games remaining in the season following an Australian record unbeaten run, and later completed the Premiership and Championship double by beating the Central Coast Mariners in the Grand Final.

A new rule at the start of the season allows for two marquee players to be signed without salary cap restraints so long as one is Australian with a certain number of qualifications to be determined by FFA.

The following do not fill a Visa position: 1Those players who were born and started their professional career abroad but have since gained Australian Residency (and New Zealand Residency, in the case of Wellington Phoenix); 2Australian residents (and New Zealand residents, in the case of Wellington Phoenix) who have chosen to represent another national team; 3Injury Replacement Players, or National Team Replacement Players; 4Guest Players (eligible to play a maximum of ten games)

The regular season started on Thursday, 5 August 2010 and ended on Sunday, 13 February 2011.

It was awarded to Premiers Brisbane Roar who beat last year's Champions Sydney FC by 6 points.