After a disappointing previous season, the Ducks attempted to win the Stanley Cup for the second time in franchise history.
On Tuesday, June 22, 2010, captain Scott Niedermayer announced his retirement from professional hockey, while it was reported Selanne would stay so long as the Ducks did not go into a "rebuilding" season.
Returning home, the Ducks rebounded a little bit after the horrendous first three games by beating the eventual President's Trophy winner Vancouver Canucks 4–3.
When the Ducks returned to Honda Center on the 29th, they faced the team that beat them in the Stanley Cup Finals in 2003: the New Jersey Devils.
The Devils edged the Ducks 2–1 and to round out what was a disappointing month, Anaheim lost to arch-rival San Jose on the 30th.
Back home in Southern California, the Ducks dropped the first game after Christmas to cross-town rival Los Angeles at Staples Center, but they did win the final two games of the month at Phoenix and finally back home at Honda Center over the Philadelphia Flyers.
Despite an 8–6–1 record, the Ducks were in a playoff position for most of the month of December partially thanks to the fact that they had played more games than any other Western Conference team.
Anaheim was on a long homestand during the first half of the month and started with a 1–1 record in the new year by defeating the defending champion Blackhawks and falling to the Nashville Predators in front of the smallest home crowd of the season (a mere 12,216).
Heading out on the road, the Ducks were to face the Ottawa Senators, Toronto Maple Leafs, Montreal Canadiens, and Columbus Blue Jackets.
The game at Montreal was also significant because it was Ducks centerman Saku Koivu's first time playing at the Bell Centre since he signed with Anaheim prior to the 2009–10 season.
The Canadien faithful gave Koivu an incredibly warm welcome, but in the end, the patrons at the Bell Centre were not pleased with the final result as Anaheim skated away with a 4–3 shootout victory.
Going into the All-Star Game, the Ducks had 60 points, enough to be in the top 8 and were honored to send 3 players to the festivities in Raleigh, North Carolina.
The Ducks clinched a playoff spot on Friday, April 8 after a 2–1 defeat of the Los Angeles Kings in a Freeway Face-Off matchup.
Note: GP = Games played; G = Goals; A = Assists; Pts = Points; +/− = Plus/minus; PIM = Penalty minutes
Note: GP = Games played; GS = Games Started; TOI = Time on ice (minutes); W = Wins; L = Losses; OT = Overtime losses; GA = Goals against; GAA= Goals against average; SA= Shots against; SV= Saves; Sv% = Save percentage; SO= Shutouts †Denotes player spent time with another team before joining Ducks.
With their two picks in the first round, the Ducks took Cam Fowler, a defenseman from the Windsor Spitfires of the OHL and Long Beach-native Emerson Etem, a right winger from the Medicine Hat Tigers of the WHL.