Cruz Azul began their season on July 23, 2010, against Estudiantes Tecos.

Cruz Azul played their homes games on Saturdays at 17:00 hours local time.

[1] Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Cruz Azul play three different tournaments in the 2010–11 season are Apertura 2010, CONCACAF Champions League and Clausura 2011.

Source: Competitive Matches Cruz Azul position on the Club World Ranking during the 2010-11 season, according to IFFHS.