It began on 18 July 2010 with the preliminary round and ended with the final on 25 May 2011.
Mladá Boleslav prevailed in Stadion v Jiráskově ulici, Jihlava at the 25 May 2011 Cupdefeating Sigma Olomouc, under a penalty score of 4–3.
The main date for second round matches was 1 September 2010.
Notes The Third round was played on 22 September 2010.
1The first leg between Slavia Prague and Sigma Olomouc was suspended after the first half at a score of 1–1 after Slavia supporters invaded the pitch.