The regular season began on away ice on 16 September 2010 against HV71 and concluded on 5 March 2011 away against Timrå IK.
Djurgården lost several prominent players to NHL, including Jacob Josefson, Gustaf Wesslau, Kyle Klubertanz and Andreas Engqvist.
Five players were brought up from Djurgården's youth program while one of them, goaltender Tim Sandberg, was loaned out to Sundsvall.
Due to the uncertainty regarding Marcus Nilson's participation for the coming season, Djurgården signed Daniel Widing as a replacement in August.
[4][5] Djurgårdens IF players picked in the 2011 NHL Entry Draft at the Xcel Energy Center in St. Paul, Minnesota.