The 2010–11 Duquesne Dukes men's basketball team represented Duquesne University in the 2010–11 NCAA Division I men's basketball season.

The Dukes, led by head coach Ron Everhart, played their home games at the A.J.

[1] However, they ended the regular season losing six of their last eight games.

The Dukes finished fourth in the A-10 during the regular season, but were upset in the quarterfinals of the Atlantic 10 tournament by the 12th-seeded Saint Joseph's,[2] ending their tournament run after just one game.

The Dukes won their first game in the tournament, but were eliminated in the quarterfinals of the CBI after losing to eventual tournament champion Oregon, 77–75.