2010–11 George Mason Patriots men's basketball team

Led by fourteenth-year head coach Jim Larranaga, the Patriots were members of the Colonial Athletic Association (CAA) and played home games on campus at the Patriot Center in Fairfax, Virginia.

The Patriots were upset in the semifinals of the conference tournament to fourth-seeded VCU.

GMU received an at-large bid in the NCAA tournament and were the eighth seed in the East region.

They defeated Villanova in the second round (64 teams), then fell to top-ranked Ohio State to finish at 27–7 (.794).

After the season, Larranaga left for the University of Miami and was succeeded by Paul Hewitt, previously the head coach at Georgia Tech.