The 2010–11 season is Hartlepool United's 102nd season in existence and their fourth consecutive season in League One since promotion in 2006–07.

Along with competing in League One, the club will also participate in the FA Cup, League Cup and League Trophy.

The season covers the period from 1 July 2010 to 30 June 2011.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Players may hold more than one non-FIFA nationality.