The 2010–11 Kuwaiti Premier League season was the 49th since its establishment.

The season started in August and finished in April after a 3-month break for the 2011 AFC Asian Cup played in January.

Al Salibikhaet and Al Tadamon were relegated to the Kuwaiti Division One league after finishing bottom in the 2009–10 season and relegation playoff respectively.

The two relegated teams were replaced by Kuwaiti Division One champions Al Sahel and playoff winners Al Jahra.

Al Salmiya retained Premier League status.