[4] A total of twelve teams were to contest the league, meaning the league has been reduced in size for the second consecutive season, with eleven teams from the 2009–10 season and one promoted from the 2009–10 Libyan Second Division.
Ahly Tripoli, Tahaddy and Najma were relegated from the 2009–10 Libyan Premier League after finishing in the bottom three places in the table.
Tahaddy and Najma were relegated after just one year each in the top flight, while Ahly Tripoli were relegated by the LFF following a 13-year tenure, after failing to show for two consecutive games, amid protests about unfair treatment.
Olomby were the final side to secure their place for next season, defeating Wahda 3–1 on aggregate in the Relegation Playoff.
Ahly, Najma and Tahaddy were later re-instated, as were Wahda, to make up a 16-team league for this season.