The Liga ABF 2010–11 was the 54th season of women's handball top flight in Spain since its establishment, taking place from 11 September 2010 to 14 May 2011.
Fourteen teams took part in the championship, with CBF Monóvar and CBM Murcia replacing relegated teams BM Gijón and CB Ribarroja.
[1] CBF Elda held its position as the runner-up, and BM Sagunto, Mar Alicante and BM Bera Bera also qualified for international competitions.
[2] However Remudas avoided relegation in June as CP Goya Almería sold it its spot due to financial stress.
In the EHF Cup Sagunto reached the quarter-finals, while 2010 runner-up Elda and CLeBa León didn't make it past the qualifying rounds.