The 2010–11 Liga Nacional de Ascenso season is the thirteenth edition since its establishment in 1996.
A total of 16 teams contest the league, 10 of which returned from the 2009 season, 1 of which was promoted from Copa Rommel Fernández, and 5 of which have been invited to participate as part of the league's expansion project.
The original match between Río Abajo and Colón C-3 was played on September 26 at 19:00 (UTC-5) at Cancha de Entrenamiento Luis Tapia, but it was suspended at the 65th minute by the referee Luis Rodríguez because of violence in the stands perpetuated by the team's supporters.
[4] At the time of the suspension, Río Abajo was winning 1-0 but the rematch was scheduled to start from 0.
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