The 2010–11 season was Lille's 51st season in the top division of French football, and the 9th year of their current spell.

This season was one of the most important in the club's history, as they won both Ligue 1 and the Coupe de France, titles which they had not conquered since 1954 and 1955, respectively.

[1][2] Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Players may hold more than one non-FIFA nationality.

Source: Competitive matches