The Tigers finished in second place in C-USA, but were upset in the quarterfinals of the conference tournament by 7 seed and ultimate champion, Houston.

Sources: The Tigers began the 2010–2011 season ranked 19th in the AP Poll and the pre-season favorite to win the Conference USA championship.

[4] The team announced on December 10, 2010 that junior forward Wesley Witherspoon would be out a number of weeks as a result of knee surgery.

[5] On December 12, 2010, junior forward Angel Garcia left the Tigers to play professionally in Spain.

However, beset by injuries, transfers, suspensions, and inconsistent play from their heralded freshmen and upperclassmen, the Tigers underachieved relative to their pre-season expectations during a majority of their regular season schedule.