The 2010–11 Oklahoma State Cowboys basketball team represented Oklahoma State University in the 2010–11 NCAA Division I men's basketball season.

This was head coach Travis Ford's third season at Oklahoma State.

The Cowboys competed in the Big 12 Conference and played their home games at the Gallagher-Iba Arena.

They advanced to the quarterfinals of the Big 12 tournament where they lost to Kansas.

They did not receive an at-large invitation to the 2011 NCAA tournament, but did receive an invitation to the 2011 National Invitation Tournament where they lost to Washington State in the second round.