[8] Two more relegation spots were to be confirmed going into the final day of the season, with five teams (Blackburn Rovers, Wolverhampton Wanderers, Birmingham City, Blackpool, and Wigan Athletic) all at threat of the drop.

[9] Birmingham City were also down after Roman Pavlyuchenko scored an injury-time winner for Tottenham at White Hart Lane.

[10] Both of these results allowed Wolves to avoid the drop by one point, despite their loss to Blackburn, while Wigan, who were in the bottom three prior to kick-off, extended their Premier League stay to seven consecutive seasons after a 1–0 win away at Stoke City.

Also being introduced this season was the "home grown players" rule, which aims to encourage the development of young footballers at Premier League clubs.

They replaced Burnley, Hull City and Portsmouth, who were relegated to the Championship after their top flight spells of one, two and seven years respectively.

[14] Additionally, Umbro provided officials with new kits in black, lime green, yellow, red and cyan blue for the season.

[46] The Premier League Player of the Season award was won by Nemanja Vidić of Manchester United.

[50] The Premier League Golden Glove award was won by Joe Hart of Manchester City.