The 2010–11 Premier League of Bosnia and Herzegovina was the eleventh season since its original establishment and the ninth as a unified country-wide league.
Željezničar were the defending champions, having won their fourth championship title in the 2009–10 season.
The league was won by Borac Banja Luka; Budućnost Banovići and Drina Zvornik were relegated to the second-level leagues.
They were replaced by the champions of the two second-level leagues, Budućnost Banovići from the Prva Liga BiH and Drina Zvornik from the Prva Liga RS.
As of 19 May 2011; Source: NFSBiH Goalkeepers: Asmir Avdukić (30/0) Defenders: Vule Trivunović (15/1) ; Vukašin Benović (10/0) ; Draško Žarić (10/0) ; Milan Stupar (22/1) ; Leonid Ćorić (21/0) ; Perica Stančeski (13/1) ; Dragoslav Stakić (14/0) ; Bojan Tetrić (13/0) ; Duško Sakan (11/0) ; Nemanja Damjanović (12/0) Midfielders: Branislav Krunić (15/2) ; Darko Maletić (21/6) ; Milan Muminović (10/0) ; Bojan Puzigaća (12/2) ; Aleksandar Petrović (1/0) ; Siniša Dujković (2/0) ; Dražen Međedović (13/0) ; Milan Srećo (10/1) ; Borislav Mikić (24/1) ; Srđan Grahovac (24/1) ; Boris Raspudić (26/1) Forwards: Nemanja Vidaković (14/2) ; Ljubiša Vukelja (10/2) ; Duško Stajić (26/3) ; Stevo Nikolić (26/10) ; Rade Veljović (13/2) .