The 2010–11 season was Sheffield Wednesday's first season in the third tier of English football since 2005 and their 109th season in the Football League.

Sheffield Wednesday's 2010/11 fixtures: Sheffield Wednesday's 2010/11 FA Cup fixtures: Sheffield Wednesday's 2010–11 League Cup fixtures: Sheffield Wednesday's 2010–11 Football League Trophy fixtures: Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Players may hold more than one non-FIFA nationality.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Players may hold more than one non-FIFA nationality.