The 2010–11 Slovenian Football Cup was the 20th season of the Slovenian Football Cup, Slovenia's football knockout competition.
Maribor were the defending champions, having won their sixth Slovenian Cup the previous season.
Winners and runners-up of the regional MNZ cups.
Gorica, Koper, Maribor and Olimpija received byes to this round.
The first legs took place on 20 October 2010 and the second legs took place on 27 October and 3 November 2010.