[2] The champions of this season, FC Lausanne-Sport, earned promotion to the 2011–12 Super League.
The runners-up Servette won the promotion/relegation playoff against the 9th-placed team of the 2010–11 Super League, AC Bellinzona.
They were replaced by FC Aarau, who were relegated after finishing the 2009–10 Super League in last place.
They were replaced by FC Chiasso and SR Delémont, who emerged victorious from the eight-team 1.
Including matches played on 21 May 2011; Source: Swiss Football League