The 2010–11 Toto Cup Leumit was the twenty-nine season of the third most important football tournament in Israel since its introduction and seventh under the current format.
First, sixteen Liga Leumit teams were divided into four groups.
The defending champions were Ironi Kiryat Shmona, making it their second Toto Cup title overall, due to the promotion in the last season the club could not defend their title.
It won on 15 December 2010 by Ironi Ramat HaSharon.
1 Score after 90 minutes The matches were played on 30 November 2010.